4-(ChloroMethyl)-N-cyclopropylbenzaMide synthesis
- Product Name:4-(ChloroMethyl)-N-cyclopropylbenzaMide
- CAS Number:873371-67-6
- Molecular formula:C11H12ClNO
- Molecular Weight:209.67
876-08-4
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$11.00/25g
765-30-0
486 suppliers
$10.00/25g
873371-67-6
11 suppliers
$75.00/1g
Yield:873371-67-6 95%
Reaction Conditions:
with N-ethyl-N,N-diisopropylamine in dichloromethane; for 1 h;
Steps:
A 4-Chloromethyl-N-cyclopropyl-benzamide
EXAMPLE A 4-Chloromethyl-N-cyclopropyl-benzamide 4-Chloromethyl-benzoyl chloride (2.82 g, 15 mmol) and cyclopropylamine (1.26 ml, 18 mmol) were reacted in CH2Cl2 (30 ml) and in the presence of Hünig's base (3.1 ml, 18 mmol) for 1 h. A precipitate was formed which was resolubilized by adding ethyl acetate. The reaction mixture was washed with a 5% KHSO4/10% K2SO4 solution, NaCl sat.
References:
US2007/37789,2007,A1 Location in patent:Page/Page column 9-10
1642-81-5
384 suppliers
$17.00/5g
765-30-0
486 suppliers
$10.00/25g
873371-67-6
11 suppliers
$75.00/1g