ChemicalBook CAS DataBase List 4-CHLOROPHENYL BENZOATE

4-CHLOROPHENYL BENZOATE synthesis

7synthesis methods

Product Name:4-CHLOROPHENYL BENZOATE
CAS Number:2005-08-5
Molecular formula:C13H9ClO2
Molecular Weight:232.66

55-21-0 Synthesis

55-21-0
385 suppliers
$5.00/5 g

106-48-9
471 suppliers
$10.00/5 g

2005-08-5
56 suppliers
$47.00/10 g

Yield: 71%

Reaction Conditions:

with iron(III) nitrate hexahydrate;trifluorormethanesulfonic acid in o-xylene at 80;

Steps:

9 Synthesis of p-chlorophenyl benzoate
In a reaction tube containing 70 mol% of Fe (NO3) 3 · 6H20 catalyst, 0.2 mmol of benzamide, 20 mol% of trifluoromethanesulfonic acid, 2 ml Solvent 1,2-xylene, 0.2mmo 1 p-chlorophenol, reacted at 80 ° C. After the reaction, the mixture was washed with water or a saturated salt solution, extracted with chloroform, dried and concentrated under reduced pressure to remove the solvent. Chromatographic separation gave the target product: 71% yield.

References:

Hubei College Of Sciences And Technology;Chen Xiuling;Sun Shaofa;Wu Minghu;Wang Jian;Guo Haibing;Li Yan CN106831285, 2017, A Location in patent:Paragraph 0051-0053

591-50-4 Synthesis