ChemicalBook CAS DataBase List 4-Cyano-4'-ethylbiphenyl

4-Cyano-4'-ethylbiphenyl synthesis

9synthesis methods

Product Name:4-Cyano-4'-ethylbiphenyl
CAS Number:58743-75-2
Molecular formula:C15H13N
Molecular Weight:207.27

623-00-7
467 suppliers
$6.00/10g

63139-21-9 Synthesis

63139-21-9
296 suppliers
$5.00/250mg

58743-75-2
211 suppliers
$43.70/1g

Yield:58743-75-2 98%

Reaction Conditions:

with potassium carbonate in water;N,N-dimethyl-formamide at 80; for 2.3 h;Suzuki Coupling;

Steps:

2.5. General procedure for the Suzuki reaction of aryl halides witharylboronic acids

General procedure: The aryl halide (0.5 mmol), arylboronic acid (0.75 mmol), Cell-NHC-Pd (0.75 mol%), K₂CO₃(1 mmol) and DMF:H₂O (1:1) (2.5 mL)were successively added into a 25 mL round bottom flask. The mixture was stirred vigorously at 80 °C for the varying specific length of time based on each different substrate. After reaction completion, the solid catalyst was filtered off. The filtrate was extracted with ethyl acetate (3 × 5 mL), washed with water and brine three times, and then dried over anhydrous MgSO₄. The MgSO₄ was then filtered off. After removal of the solvent, the crude product was purified by preparative TLC (eluent: petroleum ether/ethyl acetate, 20/1) to give the desired product and calculate the yield.

References:

Wang, Xiaoxia;Hu, Peibo;Xue, Fengjun;Wei, Yuping [Carbohydrate Polymers,2014,vol. 114,p. 476 - 483]

63139-21-9 Synthesis

63139-21-9
296 suppliers
$5.00/250mg

767-00-0 Synthesis