4-[(cyclopropylmethyl)amino]benzonitrile synthesis
1synthesis methods
- Product Name:4-[(cyclopropylmethyl)amino]benzonitrile
- CAS Number:1019607-58-9
- Molecular formula:C11H12N2
- Molecular Weight:172.2264
Yield:1019607-58-9 99%
Reaction Conditions:
with copper(l) iodide;dimethylaminoacetic acid;tetra(n-butyl)phosphonium malonate in dimethyl sulfoxide at 25; for 24 h;Inert atmosphere;
References:
Yang, Chu-Ting;Fu, Yao;Huang, Yao-Bing;Yi, Jun;Guo, Qing-Xiang;Liu, Lei [Angewandte Chemie - International Edition,2009,vol. 48,# 40,p. 7398 - 7401][Angewandte Chemie,2009,vol. 121,# 40,p. 7534 - 7537] Location in patent:supporting information; experimental part