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26672-58-2

4'-(Dimethylamino)propiophenone synthesis

11synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: iodine; zinc powder / tetrahydrofuran / 1 h / Inert atmosphere
1.2: 0 - 22 °C / Inert atmosphere
2.1: manganese(III) triacetate; 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 1.5 h / 22 °C / Inert atmosphere

References:

Cosner, Casey C.;Helquist, Paul [Organic Letters,2011,vol. 13,# 14,p. 3564 - 3567]