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ChemicalBook CAS DataBase List 4-Dodecenal, (4Z)-

4-Dodecenal, (4Z)- synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 5 steps
1.1: phosphorus tribromide / diethyl ether / 0 - 20 °C
2.1: sodium hydride / mineral oil; tetrahydrofuran / 30 min / 20 °C
2.2: 15 h / 20 °C
3.1: lithium bromide; sodium chloride / dimethyl sulfoxide; water / 6 h / 165 °C
4.1: lithium aluminium tetrahydride / diethyl ether / 5 h / 20 °C
5.1: pyridinium chlorochromate / dichloromethane / 1 h / 20 °C

References:

Perrin, Coline;Baldovini, Nicolas [Chemistry and biodiversity,2023,vol. 20,# 2,art. no. E202200817]