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ChemicalBook CAS DataBase List 4-ETHOXY-3-METHOXYBENZONITRILE

4-ETHOXY-3-METHOXYBENZONITRILE synthesis

10synthesis methods
-

Yield:81259-56-5 100%

Reaction Conditions:

Stage #1: 3-methoxy-4-hydroxybenzonitrilewith sodium hydride in N,N-dimethyl-formamide at 0; for 0.583333 h;
Stage #2: ethyl bromide in N,N-dimethyl-formamide at 0 - 20;

References:

Ma, Anqi;Yu, Wenyu;Xiong, Yan;Butler, Kyle V.;Brown, Peter J.;Jin, Jian [MedChemComm,2014,vol. 5,# 12,p. 1892 - 1898] Location in patent:supporting information