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ChemicalBook CAS DataBase List 4-ethoxy-N-methoxy-N-methylbenzamide
1221341-06-5

4-ethoxy-N-methoxy-N-methylbenzamide synthesis

1synthesis methods
-

Yield:-

Reaction Conditions:

Stage #1: 4-(ethoxy)benzoic acidwith oxalyl dichloride;N,N-dimethyl-formamide in dichloromethane at 20; for 3 h;Inert atmosphere;
Stage #2: O,N-dimethyl-hydroxylamine hydrochloridewith triethylamine in dichloromethane at 0;Inert atmosphere;

References:

Komatsuda, Masaaki;Kondo, Hiroki;Ohki, Hugo;Suto, Ayane;Yamaguchi, Junichiro [Organic Letters,2022,vol. 24,# 17,p. 3270 - 3274] Location in patent:supporting information