4-Ethoxyphenylboronic acid synthesis
1synthesis methods
- Product Name:4-Ethoxyphenylboronic acid
- CAS Number:22237-13-4
- Molecular formula:C8H11BO3
- Molecular Weight:165.98
Yield:-
Reaction Conditions:
with potassium carbonate in acetone;
Steps:
For compounds (57, 60-62, 106-109, 159, 160) the commercially available 4-fluorophenylboronic acid was treated with EtI/K2CO3 in acetone at reflux for 12 hr. (See above compound 42) to give the alkylated product 4-ethoxyphenylboronic acid. This boronic acid was used at the Suzuki coupling stage in the synthesis of compounds (57, 60-62, 106-109, 159, 160).
References:
US2006/4002,2006,A1 Location in patent:Page/Page column 41