4-ethyl-2,6-dihydroxynicotinonitrile synthesis
1synthesis methods
- Product Name:4-ethyl-2,6-dihydroxynicotinonitrile
- CAS Number:23328-64-5
- Molecular formula:C8H8N2O2
- Molecular Weight:164.16
Yield:23328-64-5 41%
Reaction Conditions:
with potassium hydroxide in methanol at 65; for 2 h;
References:
Renck, Daiana;MacHado, Pablo;Souto, Andre A.;Rosado, Leonardo A.;Erig, Thais;Campos, Maria M.;Farias, Caroline B.;Roesler, Rafael;Timmers, Luis F. S. M.;De Souza, Osmar N.;Santos, Diogenes S.;Basso, Luiz A. [Journal of Medicinal Chemistry,2013,vol. 56,# 21,p. 8892 - 8902] Location in patent:supporting information