![](/CAS/GIF/27465-51-6.gif)
4'-Ethylpropiophenone synthesis
- Product Name:4'-Ethylpropiophenone
- CAS Number:27465-51-6
- Molecular formula:C11H14O
- Molecular Weight:162.23
![Methanol](/CAS/GIF/67-56-1.gif)
67-56-1
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$9.00/25ml
![1-(4-Ethylphenyl)ethanol](/CAS/20180531/GIF/33967-18-9.gif)
33967-18-9
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$91.67/0.5g
![4'-Ethylpropiophenone](/CAS/GIF/27465-51-6.gif)
27465-51-6
275 suppliers
$11.00/5g
Yield:27465-51-6 88%
Reaction Conditions:
with chlorine[2-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxypyridine](pentamethylcyclopentadienyl)iridium(III) chloride;potassium hydroxide in water at 80;Schlenk technique;Inert atmosphere;
Steps:
14
In a 10 mL Schlenk tube, methanol (1.1 mmol), 4-ethylphenethyl alcohol (1.0 mmol), KOH (1.1 mmol), H2O (2.0 mL) and TC-6 (0.1 mol%) were added. Under the protection of nitrogen, heat to 80°C for reaction. After completion, it was extracted with ethyl acetate (3×5.0 mL), the organic layers were combined, dried over anhydrous magnesium sulfate, and the solvent was concentrated under reduced pressure to obtain a crude product. The crude product was purified with a mixture of ethyl acetate/petroleum ether (1/50) as the eluent and purified by silica gel chromatography to obtain a pure product with a yield of 88%.
References:
CN112047797,2020,A Location in patent:Paragraph 0165-0172
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![(2RS)-2-(4-ETHYLPHENYL)PROPANOIC ACID](/CAS/GIF/3585-52-2.gif)
3585-52-2
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$60.00/10mg
![4'-Ethylpropiophenone](/CAS/GIF/27465-51-6.gif)
27465-51-6
275 suppliers
$11.00/5g
![Benzene, 1-ethyl-4-(1-methoxyethenyl)-](/CAS/20210305/GIF/104037-22-1.gif)
104037-22-1
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![4'-Ethylpropiophenone](/CAS/GIF/27465-51-6.gif)
27465-51-6
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$11.00/5g
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100-41-4
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$5.00/5G
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123-62-6
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$17.00/25g
![4'-Ethylpropiophenone](/CAS/GIF/27465-51-6.gif)
27465-51-6
275 suppliers
$11.00/5g