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4-FLUORO-3-TRIFLUOROMETHYLPHENYL ISOTHI& synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 1,4-diaza-bicyclo[2.2.2]octane / toluene / 8 h / 20 °C
2: bis(trichloromethyl) carbonate / dichloromethane / 8 h / -5 °C / Reflux

References:

Kong, Xiangkai;Yao, Zeyu;He, Zuopeng;Xu, Wenfang;Yao, Jianwen [MedChemComm,2015,vol. 6,# 5,p. 867 - 870]

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