![](/CAS/GIF/371-40-4.gif)
4-Fluoroaniline synthesis
- Product Name:4-Fluoroaniline
- CAS Number:371-40-4
- Molecular formula:C6H6FN
- Molecular Weight:111.12
![4-Fluoronitrobenzene](/CAS/GIF/350-46-9.gif)
350-46-9
515 suppliers
$10.60/1gm:
![4-Fluoroaniline](/CAS/GIF/371-40-4.gif)
371-40-4
405 suppliers
$5.00/5G
Yield:371-40-4 100%
Reaction Conditions:
with 10% Pd/C;hydrogen in methanol at 20; for 3 h;
Steps:
2 4.2.2. 4-Fluoroaniline (4a)
To a solution of 4-fluoro-1-nitrobenzene (3a, 212 mL, 2.00 mmol)in MeOH (10 mL) was added 10% Pd/C (21 mg, 0.020 mmol). Thereaction mixture was stirred and bubbled with H2 at room temperaturefor 3 h. The solids were filtered off and washed with DCM(25 mL). The filtrate and DCM washing were combined andconcentrated under reduced pressure to give 4a as a clear yellow oil(222 mg, 100%).
References:
Teo, Theodosia;Yang, Yuchao;Yu, Mingfeng;Basnet, Sunita K.C.;Gillam, Todd;Hou, Jinqiang;Schmid, Raffaella M.;Kumarasiri, Malika;Diab, Sarah;Albrecht, Hugo;Sykes, Matthew J.;Wang, Shudong [European Journal of Medicinal Chemistry,2015,vol. 103,p. 539 - 550]
![4-Bromofluorobenzene](/CAS/GIF/460-00-4.gif)
460-00-4
614 suppliers
$6.00/10g
![4-Fluoroaniline](/CAS/GIF/371-40-4.gif)
371-40-4
405 suppliers
$5.00/5G
![1-Fluoro-4-iodobenzene](/CAS/GIF/352-34-1.gif)
352-34-1
368 suppliers
$7.00/5g
![4-Fluoroaniline](/CAS/GIF/371-40-4.gif)
371-40-4
405 suppliers
$5.00/5G
![1-Azido-4-fluorobenzene solution](/CAS/GIF/3296-02-4.gif)
3296-02-4
7 suppliers
$220.00/500mg
![4-Fluoroaniline](/CAS/GIF/371-40-4.gif)
371-40-4
405 suppliers
$5.00/5G
![4-Fluorobenzeneboronic acid](/CAS/GIF/1765-93-1.gif)
1765-93-1
550 suppliers
$9.00/1g
![4-Fluoroaniline](/CAS/GIF/371-40-4.gif)
371-40-4
405 suppliers
$5.00/5G