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ChemicalBook CAS DataBase List 4-FLUOROBENZENESULFINIC ACID SODIUM SALT
824-80-6

4-FLUOROBENZENESULFINIC ACID SODIUM SALT synthesis

7synthesis methods
-

Yield: 99%

Reaction Conditions:

with sodium hydrogencarbonate;sodium sulfite in water at 80; for 4 h;

Steps:

3
Take 250mL of mono vial,P-fluorobenzenesulfonyl chloride (48.5 mmol, 9.4 g, 1.0 equiv) was added,Sodium sulfite (97 mmol, 12.2 g, 2.0 equiv),Sodium bicarbonate (97 mmol, 8.1 g, 2.0 equiv)Add 60 mL of water,Equipped with reflux condenser,80 ° C for 4 h.The reaction ends,Dry water,Add methanol dissolved to filter,And then spin dry methanol to white solid 10.2g,Yield 99%.

References:

Chinese Academy Of Sciences Shanghai Organic Chemistry Institute;Shen Qilong;Wu Jiang;Zhao Qunchao CN107033046, 2017, A Location in patent:Paragraph 0192; 0193; 0194