4-FORMYLPHENYL THIOPHENE-2-CARBOXYLATE synthesis
- Product Name:4-FORMYLPHENYL THIOPHENE-2-CARBOXYLATE
- CAS Number:331948-76-6
- Molecular formula:C12H8O3S
- Molecular Weight:232.26
5271-67-0
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$5.00/1g
123-08-0
903 suppliers
$5.00/10g
331948-76-6
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$144.00/500mg
Yield:331948-76-6 87%
Reaction Conditions:
with triethylamine in tetrahydrofuran at 20; for 3.5 h;Reflux;
Steps:
2.2.1. General procedure for synthesis of compounds 1a-h
General procedure: Hydroxy benzaldehydes (4-hydroxybenzaldehyde, salicylalde- hyde, vanillin) (10 mmol) were dissolved in 20 ml THF separately and the solutions were then put into an ice bath. 2-furoyl chlo- ride, thiophene-2-carbonyl chloride, and tosyl chloride (10 mmol) were added to these solutions in cold. Triethylamine (11 mmol) in 20 mL THF was added to each of the solutions by dropwise and mixed for half an hour at room temperature. After undergoing re- flux for three hours, the solvent was removed under reduced pres- sure. Formed residue was washed with cold water to remove tri- ethylammonium chloride salt and recrystallized from ethanol.
References:
Tokal?, Feyzi Sinan;Taslimi, Parham;Usanmaz, Hande;Karaman, Muhammet;?endil, K?v?lc?m [Journal of Molecular Structure,2021,vol. 1231,art. no. 129666]
527-72-0
483 suppliers
$5.00/10g
123-08-0
903 suppliers
$5.00/10g
331948-76-6
11 suppliers
$144.00/500mg
527-72-0
483 suppliers
$5.00/10g
331948-76-6
11 suppliers
$144.00/500mg
98-03-3
530 suppliers
$5.00/25g
331948-76-6
11 suppliers
$144.00/500mg