4-hydroxy-3-(trifluoromethoxy)benzonitrile synthesis
- Product Name:4-hydroxy-3-(trifluoromethoxy)benzonitrile
- CAS Number:1093397-72-8
- Molecular formula:C8H4F3NO2
- Molecular Weight:203.12
53104-95-3
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Yield:-
Steps:
Multi-step reaction with 3 steps
1: Jones reagent / acetone / 1 h / 0 - 20 °C
2: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; ammonium chloride; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2 h / 20 °C
3: 1,3,5-trichloro-2,4,6-triazine / N,N-dimethyl-formamide
References:
WO2008/156715,2008,A1
1093397-67-1
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1093397-72-8
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