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4-(isoxazol-4-yl)-2-(methylthio)pyrimidine synthesis

1synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: oxalyl dichloride / chloroform / 0.5 h / 0 - 45 °C
1.2: 16 h / 0 - 45 °C
2.1: hydroxylamine hydrochloride; sodium carbonate / water / 5 h / 20 °C

References:

US2017/8904,2017,A1