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4-Isoxazolecarbothioamide,5-amino-3-methyl-(9CI) synthesis

1synthesis methods
2-Butenethioamide, 2-cyano-3-ethoxy-, (2E)-

116595-42-7
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4-Isoxazolecarbothioamide,5-amino-3-methyl-(9CI)

130783-67-4
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Yield:130783-67-4 72%

Reaction Conditions:

with 1,1,3,3-tetramethylguanidine;hydroxylamine hydrochloride in chloroform; for 2 h;

References:

Vicentini, C. B.;Veronese, A. C.;Poli, T.;Guarneri, M.;Giori, P. [Journal of Heterocyclic Chemistry,1990,vol. 27,# 5,p. 1481 - 1484]