4-Methoxy-7H- Pyrrolo[2,3-d] pyriMidin-2-aMine synthesis

3synthesis methods

Product Name:4-Methoxy-7H- Pyrrolo[2,3-d] pyriMidin-2-aMine
CAS Number:84955-32-8
Molecular formula:C7H8N4O
Molecular Weight:164.16

124-41-4 Synthesis

124-41-4
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84955-31-7 Synthesis

2-Amino-4-chloropyrrolo[2,3-d]pyrimidine

84955-31-7
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$5.00/250mg

4-Methoxy-7H- Pyrrolo[2,3-d] pyriMidin-2-aMine

84955-32-8
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Yield:84955-32-8 164 mg

Reaction Conditions:

in methanol at 20;

Steps:

12.1 Step 1: Synthesis of 4-methoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amine (E47)

A 30% sodium methoxide solution in methanol (400 mg, 2.22 mmol) was added to an eggplant flask, and 10 mLof methanol was added. 4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine (168 mg, 1.00 mmol) was added andstirred at room temperature overnight. The solvent was evaporated to dryness over rotary evaporation, water wasadded, and ethyl acetate was evaporated. The target compound was obtained in 164 mg.

References:

CN109810110,2019,A Location in patent:Paragraph 0174-0177

7355-55-7 Synthesis

2-Amino-4-hydroxypyrrolo[2,3-d]pyrimidine

7355-55-7
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$14.00/250mg

84955-32-8
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References

Ethanol, 2-[(2-amino-7H-pyrrolo[2,3-d]pyrimidin-4-yl)thio]-

84981-48-6
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84955-32-8
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References