ChemicalBook CAS DataBase List (4-METHYL-PIPERAZIN-1-YL)-ACETIC ACID

(4-METHYL-PIPERAZIN-1-YL)-ACETIC ACID synthesis

7synthesis methods

Product Name:(4-METHYL-PIPERAZIN-1-YL)-ACETIC ACID
CAS Number:54699-92-2
Molecular formula:C7H14N2O2
Molecular Weight:158.2

60-29-7
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$30.00/50g

54699-92-2
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$8.00/250mg

Yield: 90%

Reaction Conditions:

in 1-acetoxy-2-(4-methyl-piperazino)-ethane;water

Steps:

3 Example 3
Example 3 Preparation of (4-methylpiperazinyl) acetic acid (VII) A 22 g solution of (4-methylpiperaziny) ethyl acetate (VI) in 500 ml of water was stirred at the reflux temperature of the solvent for 2 h. The reaction mixture was evaporated to dryness, thus obtaining a residue which, by grinding with a 8:2 diethylether/acetone mixture, provided 16.75 g (yield 90%) of a white solid with a melting point of 160-2 °C, identified as (4-methylpiperazinyl) acetic acid (VII).

References:

LABORATORIOS RUBIO, S.A. EP693481, 1996, A1