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4-(N-Acetyl)piperidinyl 2-(5-Methoxy)phenol Ketone synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: SOCl2 / 1,2-dichloro-ethane / 40 - 65 °C
2: AlCl3 / 2 h / Heating

References:

Strupczewski, Joseph T.;Allen, Richard C.;Gardner, Beth Ann;Schmid, Blaine L.;Stache, Ulrich;et al. [Journal of Medicinal Chemistry,1985,vol. 28,# 6,p. 761 - 769]