![](/CAS/GIF/66052-06-0.gif)
4-N-HEXYLOXYBENZONITRILE synthesis
- Product Name:4-N-HEXYLOXYBENZONITRILE
- CAS Number:66052-06-0
- Molecular formula:C13H17NO
- Molecular Weight:203.28
![1-Bromohexane](/CAS/GIF/111-25-1.gif)
111-25-1
314 suppliers
$10.00/5g
![4-Cyanophenol](/CAS/GIF/767-00-0.gif)
767-00-0
558 suppliers
$6.00/25g
![4-N-HEXYLOXYBENZONITRILE](/CAS/GIF/66052-06-0.gif)
66052-06-0
27 suppliers
$110.00/50mg
Yield:66052-06-0 100%
Reaction Conditions:
in potassium carbonate;
Steps:
34.A A.
A. 4-(Hexyloxy)Benzonitrile A solution of 4-cyanophenol (20 g, 168 mmol) in dimethylformamaide was treated with potassium carbonate (2 eq., 338 mmol, 47 g) and 1-bromohexane (1.1 eq., 185 mmol, 35 mL) and stirred at room temperature for 18 hours. The solid was filtered off and the solution was partitioned between ethyl acetate and 1 N HCl. The organic phase was washed with brine, dried over MgSO4, filtered and the solvent was removed to give compound 2 (45 g, >100%).
References:
US2002/137968,2002,A1
![4-Cyanophenol](/CAS/GIF/767-00-0.gif)
767-00-0
558 suppliers
$6.00/25g
![1-Hexanol](/CAS/GIF/111-27-3.gif)
111-27-3
496 suppliers
$5.00/25g
![4-N-HEXYLOXYBENZONITRILE](/CAS/GIF/66052-06-0.gif)
66052-06-0
27 suppliers
$110.00/50mg
![4-Chlorobenzonitrile](/CAS/GIF/623-03-0.gif)
623-03-0
446 suppliers
$6.00/25g
![1-Hexanol](/CAS/GIF/111-27-3.gif)
111-27-3
496 suppliers
$5.00/25g
![4-N-HEXYLOXYBENZONITRILE](/CAS/GIF/66052-06-0.gif)
66052-06-0
27 suppliers
$110.00/50mg
![4-Bromobenzonitrile](/CAS/GIF/623-00-7.gif)
623-00-7
469 suppliers
$6.00/10g
![1-Hexanol](/CAS/GIF/111-27-3.gif)
111-27-3
496 suppliers
$5.00/25g
![4-N-HEXYLOXYBENZONITRILE](/CAS/GIF/66052-06-0.gif)
66052-06-0
27 suppliers
$110.00/50mg
![4-Bromobenzonitrile](/CAS/GIF/623-00-7.gif)
623-00-7
469 suppliers
$6.00/10g
![4-N-HEXYLOXYBENZONITRILE](/CAS/GIF/66052-06-0.gif)
66052-06-0
27 suppliers
$110.00/50mg