![](/CAS/GIF/29968-78-3.gif)
4-Nitrophenethylamine hydrochloride synthesis
- Product Name:4-Nitrophenethylamine hydrochloride
- CAS Number:29968-78-3
- Molecular formula:C8H11ClN2O2
- Molecular Weight:202.64
![N-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE](/CAS/GIF/6270-07-1.gif)
6270-07-1
85 suppliers
$28.00/250mg
![4-Nitrophenethylamine hydrochloride](/CAS/GIF/29968-78-3.gif)
29968-78-3
426 suppliers
$18.00/5g
Yield:29968-78-3 84.7%
Reaction Conditions:
with hydrogenchloride in ethanol;water; pH=1; for 20 h;Reflux;Large scale;
Steps:
2
140 kg of intermediate 2 was dissolved in 190 kg of ethanol in a reaction kettle, and dissolved under constant stirring, the pH was adjusted to 1 with 2mol/L hydrochloric acid, and the reaction solution was heated to 80° C for 20 hours, after the reaction was completed, the reaction solution was cooled to room temperature and solids precipitated, the crude product was recrystallized from methanol to give 116 Kg of finished p-nitrophenylethylamine hydrochloride after filtration and centrifugation, the final product purity was 99.6%, and the yield of this step was 84.7%.
References:
CN107759477,2018,A Location in patent:Paragraph 0063
![Propanamide, N-[2-(4-nitrophenyl)ethyl]-](/CAS/20210305/GIF/250266-58-1.gif)
250266-58-1
1 suppliers
inquiry
![4-Nitrophenethylamine hydrochloride](/CAS/GIF/29968-78-3.gif)
29968-78-3
426 suppliers
$18.00/5g
![Benzene, 1-(2-azidoethyl)-4-nitro-](/CAS/20180531/GIF/70079-91-3.gif)
70079-91-3
0 suppliers
inquiry
![4-Nitrophenethylamine hydrochloride](/CAS/GIF/29968-78-3.gif)
29968-78-3
426 suppliers
$18.00/5g
![2-Phenylethylamine hydrochloride](/CAS/GIF/156-28-5.gif)
156-28-5
264 suppliers
$21.00/100g
![4-Nitrophenethylamine hydrochloride](/CAS/GIF/29968-78-3.gif)
29968-78-3
426 suppliers
$18.00/5g
![4-Nitrobenzeneethanol](/CAS/GIF/100-27-6.gif)
100-27-6
241 suppliers
$6.00/5g
![4-Nitrophenethylamine hydrochloride](/CAS/GIF/29968-78-3.gif)
29968-78-3
426 suppliers
$18.00/5g