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4-Phenyl-2H-1,2,3-benzothiadiazine1,1-dioxide synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: acetic acid / 12 h / 80 - 90 °C / Inert atmosphere
2.1: N,N,N,N,-tetramethylethylenediamine; lithium diisopropyl amide / tetrahydrofuran / 1.5 h / 0 °C / Inert atmosphere
2.2: Inert atmosphere

References:

Kacem, Yakdhane;Hassine, Béchir Ben [Tetrahedron Letters,2013,vol. 54,# 31,p. 4023 - 4025]