4-PHENYL-CYCLOHEXANEACETIC ACID ETHYL ESTER synthesis

3synthesis methods

Product Name:4-PHENYL-CYCLOHEXANEACETIC ACID ETHYL ESTER
CAS Number:411238-92-1
Molecular formula:C16H22O2
Molecular Weight:246.34

2-(4-PHENYLCYCLOHEXYLIDENE)-ACETIC ACID ETHYL ESTER

115880-04-1
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4-PHENYL-CYCLOHEXANEACETIC ACID ETHYL ESTER

411238-92-1
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Yield: 99%

Reaction Conditions:

with 5%-palladium/activated carbon;hydrogen in methanol

Steps:

1.2 Step 2: Synthesis of Compound 1.2
Compound 1.1 (5.0 g, 20.5 mmol) was dissolved in methanol (100 mL) and Pd/C (5% wet palladium on carbon) was added,200mg). The reaction was then replaced with hydrogen three times and stirred under a hydrogen system (hydrogen balloon) overnight. After filtration, the filter cake was washed with methanol, and the filtrate was evaporated under reduced pressure to give compound 1.2 (5.0 g, yield: 99%) as a white solid.

References:

Shanghai Dinuo Pharmaceutical Technology Co., Ltd.;Liu Shengyang;Li Qun CN107674029, 2018, A Location in patent:Paragraph 0179; 0180; 0183; 0184

4894-75-1
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411238-92-1
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References

92-68-2
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$144.00/250mg

411238-92-1
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References