ChemicalBook CAS DataBase List 4-Phenylfurazanamine

4-Phenylfurazanamine synthesis

11synthesis methods

Product Name:4-Phenylfurazanamine
CAS Number:10349-14-1
Molecular formula:C8H7N3O
Molecular Weight:161.16

1,2,5-Oxadiazole, 3-nitro-4-phenyl-, 2-oxide

76016-69-8
0 suppliers
inquiry

10349-14-1
11 suppliers
inquiry

Yield:10349-14-1 81%

Reaction Conditions:

with hydrogenchloride;tin(ll) chloride at 20; for 1 h;chemoselective reaction;

Steps:

Reduction of 3- and 4-Nitrofuroxans; General Procedure

General procedure: SnCl 2 (1.90 g, 10 mmol) was added to a vigorously stirred mixture ofthe corresponding nitrofuroxan 1 or 2 (1 mmol) and concd HCl (7 mL)in one portion at room temperature. The reaction mixture was stirredfor 1 h, then poured into H 2 O (15 mL) and extracted with EtOAc(3 × 15 mL). The combined organic layers were washed with brine (30mL) and dried over MgSO 4 . The drying agent was removed by filtra-tion, the solvent was evaporated in vacuo and the residue was tritu-rated with H 2 O. The solid product was filtered, washed with cold CH-Cl 3 (2 mL) and dried in air. 4-Amino-3-phenylfuroxan (3a) 14aYield: 173 mg (98%);

References:

Fershtat, Leonid L.;Bystrov, Dmitry M.;Zhilin, Egor S.;Makhova, Nina N. [Synthesis,2019,vol. 51,# 3,p. 747 - 756]

76016-68-7
8 suppliers
inquiry

10349-14-1
11 suppliers
inquiry

References

2-HydroxyiMino-2-phenylacetaMidoxiMe, 97%

114854-40-9
1 suppliers
inquiry

10349-14-1
11 suppliers
inquiry

References

1,2,5-Oxadiazol-3-amine, 4-phenyl-, 2-oxide

29945-54-8
0 suppliers
inquiry

10349-14-1
11 suppliers
inquiry

References

7541-02-8 Synthesis

(2Z)-2-hydroxyimino-2-phenylacetonitrile

7541-02-8
2 suppliers
inquiry

10349-14-1
11 suppliers
inquiry

References