ChemicalBook CAS DataBase List 4-phenylnaphthalen-2-ol

4-phenylnaphthalen-2-ol synthesis

12synthesis methods

Product Name:4-phenylnaphthalen-2-ol
CAS Number:36159-74-7
Molecular formula:C16H12O
Molecular Weight:220.27

93645-90-0
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36159-74-7
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Yield:36159-74-7 80%

Reaction Conditions:

with cesium fluoride in acetonitrile; for 5 h;Reflux;

Steps:

Reaction of 5a with CsF in Refluxing MeCN;

General procedure: A mixture of 5a (0.12 g, 0.50 mmol) and CsF (0.15 g, 1.0 mmol) inMeCN (5 mL) was refluxed for 5 h, and the reaction mixture waspoured into H2O and extracted with CH2Cl2 (3 × 3 mL). The combinedextracts were dried (Na2SO4), filtered, and evaporated to give almostpure 4-phenyl-2-naphthol (3aa); yield: 0.088 g (0.40 mmol, 80%).

References:

Okuma, Kentaro;Horigami, Kenta;Nagahora, Noriyoshi;Shioji, Kosei [Synthesis,2015,vol. 47,# 19,art. no. SS-2015-C0278-ST,p. 2937 - 2944]

5498-31-7 Synthesis