4-Phenyloxazole-2-thiol synthesis
2synthesis methods
- Product Name:4-Phenyloxazole-2-thiol
- CAS Number:17371-97-0
- Molecular formula:C9H7NOS
- Molecular Weight:177.22
Yield:17371-97-0 0.4 g
Reaction Conditions:
with hydrogenchloride in water at 90; for 5 h;
Steps:
36 Reference Preparation Example 36
The 2.0g of 2-hydroxy-1-phenylethanone, 2.1g of potassium thiocyanate mixture of hydrochloric acid (1N) and 30ml was stirred at 90 °C for 5 hours. The reaction mixture was allowed to cool and extracted with ethyl acetate. The organic layer was washed with saturated saline solution, dried over anhydrous magnesium sulfate, and then concentrated under reduced pressure. The residue thus obtained was washed with hexane to give 0.4g 4-phenyl-4-oxazoline-2-thione.
References:
CN105636957,2016,A Location in patent:Paragraph 0738; 0739; 0740; 0741
