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4-Piperidin-2-yl-butyric acid synthesis

6synthesis methods
diethyl 2-(2-(pyridin-2-yl)ethyl)malonate

84199-92-8
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4-Piperidin-2-yl-butyric acid

756422-50-1
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-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: aqueous NaOH
2: 160 °C
3: platinum; aqueous HCl / 20 °C / Hydrogenation

References:

Doering;Weil [Journal of the American Chemical Society,1947,vol. 69,p. 2461,2464]