4-[(piperidine-1-sulfonyl)methyl]benzonitrile synthesis
2synthesis methods
- Product Name:4-[(piperidine-1-sulfonyl)methyl]benzonitrile
- CAS Number:1029603-11-9
- Molecular formula:C13H16N2O2S
- Molecular Weight:264.3434
![Benzenesulfonic acid, 4-methyl-, 2-[(4-cyanophenyl)methylene]hydrazide](/CAS/20210305/GIF/41780-79-4.gif)
Yield:1029603-11-9 36%
Reaction Conditions:
with 1,4-diazabicyclo[2.2.2]octane-triethylenediamine-bis(sulfur dioxide);dimethyl sulfoxide at 100; for 16 h;Sealed tube;
References:
Tsai, Andy S.;Curto, John M.;Rocke, Benjamin N.;Dechert-Schmitt, Anne-Marie R.;Ingle, Gajendrasingh K.;Mascitti, Vincent [Organic Letters,2016,vol. 18,# 3,p. 508 - 511] Location in patent:supporting information