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4-(Pyridin-4-yl)-1H-pyrazole-3-carboxylic acid synthesis

5synthesis methods
117784-22-2 Synthesis
Methyl 4-(pyridin-4-yl)-1H-pyrazole-3-carboxylate

117784-22-2
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4-(Pyridin-4-yl)-1H-pyrazole-3-carboxylic acid

117784-27-7
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Yield:117784-27-7 74%

Reaction Conditions:

with potassium hydroxide at 65; for 0.5 h;

References:

Cativiela, Carlos;Villegas, Maria D. Diaz de;Mayoral, Jose A.;Avenoza, Alberto;Roy, Miguel A. [Journal of Heterocyclic Chemistry,1988,vol. 25,p. 851 - 855]