ChemicalBook CAS DataBase List 4-Pyridinecarboxylicacid,5-amino-2-methyl-(9CI)

4-Pyridinecarboxylicacid,5-amino-2-methyl-(9CI) synthesis

4synthesis methods

Product Name:4-Pyridinecarboxylicacid,5-amino-2-methyl-(9CI)
CAS Number:88482-17-1
Molecular formula:C7H8N2O2
Molecular Weight:152.15

907545-47-5 Synthesis

907545-47-5
109 suppliers
$7.00/250mg

4-Pyridinecarboxylicacid,5-amino-2-methyl-(9CI)

88482-17-1
66 suppliers
$110.00/50mg

Yield:-

Steps:

Multi-step reaction with 4 steps
1: N,N-dimethyl-formamide / 15 h / 0 - 15 °C
2: potassium carbonate; palladium diacetate; tricyclohexylphosphine tetrafluoroborate / 1,4-dioxane / 13 h / 100 °C / Inert atmosphere
3: palladium 10% on activated carbon; hydrogen / methanol / 14 h / 15 °C / 1551.49 Torr
4: sodium hydroxide; water / tetrahydrofuran / 2 h / 15 °C

References:

MERCK SHARP & DOHME CORP.;ARASAPPAN, Ashok;BUNGARD, Christopher James;FRIE, Jessica L.;HAN, Yongxin;HOYT, Scott B.;MANLEY, Peter J.;MEISSNER, Robert S.;PERKINS, James;SEBHAT, Iyassu K.;WILKENING, Robert R. WO2016/29454, 2016, A1

23056-33-9 Synthesis

23056-33-9
337 suppliers
$3.00/1g

88482-17-1
66 suppliers
$110.00/50mg

References

2-Chloro-5-nitro-isonicotinic acid methyl ester

777899-57-7
43 suppliers
inquiry

88482-17-1
66 suppliers
$110.00/50mg

References

139004-86-7 Synthesis

4-Pyridinecarboxylicacid,2-methyl-5-nitro-,methylester(9CI)

139004-86-7
15 suppliers
inquiry

88482-17-1
66 suppliers
$110.00/50mg

References