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ChemicalBook CAS DataBase List 4-Pyrimidinamine, 2-ethoxy- (9CI)
3289-48-3

4-Pyrimidinamine, 2-ethoxy- (9CI) synthesis

2synthesis methods
120362-30-3 Synthesis
Phosphonic acid, [[1-[[(methylsulfonyl)oxy]methyl]-2-(phenylmethoxy)ethoxy]methyl]-, diethyl ester-R

120362-30-3
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4-AMINO-1-ETHYL-1,2-DIHYDROPYRIMIDIN-2-ONE

25855-37-2
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120362-33-6

120362-33-6
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Phosphonic acid, [[1-[[(4-amino-2-pyrimidinyl)oxy]methyl]-2-(phenylmethoxy)ethoxy]methyl]-, diethyl ester, (R)- (9CI)

120362-34-7
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Yield:120362-33-6 40% ,120362-34-7 25%

Reaction Conditions:

with potassium carbonate in N,N-dimethyl-formamide at 90; for 18 h;

References:

Webb II;Wos;Bronson;Martin [Tetrahedron Letters,1988,vol. 29,# 43,p. 5475 - 5478]