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4-SulfaMoyl-butyric acid Methyl ester synthesis

2synthesis methods
81926-28-5 Synthesis
3-(Methoxycarbonyl)propane-1-sulphonyl chloride, Methyl 4-(chlorosulphonyl)butyrate

81926-28-5
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Yield:175476-51-4 96.9 mg

Reaction Conditions:

with ammonium hydroxide in ethyl acetate at 25;Inert atmosphere;

References:

Zhong, Dayou;Wu, Di;Zhang, Yan;Lu, Zhiwu;Usman, Muhammad;Liu, Wei;Lu, Xiuqiang;Liu, Wen-Bo [Organic Letters,2019,vol. 21,# 15,p. 5808 - 5812] Location in patent:supporting information