ChemicalBook CAS DataBase List 4-tert-Butylbenzyl bromide

4-tert-Butylbenzyl bromide synthesis

13synthesis methods

Product Name:4-tert-Butylbenzyl bromide
CAS Number:18880-00-7
Molecular formula:C11H15Br
Molecular Weight:227.14

98-51-1 Synthesis

98-51-1
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18880-00-7
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$9.00/5g

Yield:18880-00-7 100%

Reaction Conditions:

with N-Bromosuccinimide;dibenzoyl peroxide in tetrachloromethane;hexane;

Steps:

R.19 Production of N-(4-tert-Butylbenzyl)methylamine (Alternative Method)

Referential Example 19 Production of N-(4-tert-Butylbenzyl)methylamine (Alternative Method) p-tert-butyltoluene (14.8 g; 0.10 mol) was dissolved in carbon tetrachloride, and N-bromosuccinimide (17.8 g; 0.10 mol) and benzoyl peroxide (200 mg) were added thereto. The mixture was refluxed for 2 hours, and then cooled. Insoluble matter was filtered off, followed by washing with carbon tetrachloride. The filtrate was concentrated under reduced pressure, and the residue was dissolved in n-hexane, followed by drying over magnesium sulfate. The solvent was evaporated under reduced pressure, to thereby yield 22.7 g of p-tert-butylbenzyl bromide (yield: 100%).

References:

US6586633,2003,B1

877-65-6 Synthesis