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4-(tetrahydrofurfuryloxy)aniline hydrochloride synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: potassium carbonate / acetonitrile / 12 h / 80 °C
2: ammonium chloride; iron / water; methanol / 2 h / 70 °C

References:

Zhao, Dan;Huang, Shanshan;Qu, Menghua;Wang, Changyuan;Liu, Zhihao;Li, Zhen;Peng, Jinyong;Liu, Kexin;Li, Yanxia;Ma, Xiaodong;Shu, Xiaohong [European Journal of Medicinal Chemistry,2017,vol. 126,p. 444 - 455]