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4-(TRIFLUOROMETHYL)CINNAMAMIDE synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: pyridine; piperidine / isopropyl alcohol / 90 °C
2: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 20 °C
3: ammonium hydroxide

References:

CN112920133, 2021, A