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3α,11β,17,21-Tetrahydroxy-5β-pregnan-20-one 21-Acetate synthesis

3synthesis methods
-

Yield:4004-80-2 79%

Reaction Conditions:

with zinc(II) tetrahydroborate in tetrahydrofuran;diethyl ether at 20; for 0.75 h;Inert atmosphere;

References:

Okihara, Rika;Mitamura, Kuniko;Hasegawa, Maki;Mori, Megumi;Muto, Akina;Kakiyama, Genta;Ogawa, Shoujiro;Iida, Takashi;Shimada, Miki;Mano, Nariyasu;Ikegawa, Shigeo [Chemical and Pharmaceutical Bulletin,2010,vol. 58,# 3,p. 344 - 353] Location in patent:experimental part