![](/CAS/GIF/40106-14-7.gif)
2-amino-4,5,6,7,8,9-hexahydrocycloocta[b]thiophene-3-carbonitrile(SALTDATA: FREE) synthesis
1synthesis methods
- Product Name:2-amino-4,5,6,7,8,9-hexahydrocycloocta[b]thiophene-3-carbonitrile(SALTDATA: FREE)
- CAS Number:40106-14-7
- Molecular formula:C11H14N2S
- Molecular Weight:206.31
Yield: 88%
Reaction Conditions:
with morpholine;sulfur in ethanol at 70; for 18 h;Gewald reaction;
References:
Arhin, Francis;Belanger, Odette;Ciblat, Stephane;Dehbi, Mohammed;Delorme, Daniel;Dietrich, Evelyne;Dixit, Dilip;Lafontaine, Yanick;Lehoux, Dario;Liu, Jing;McKay, Geoffrey A.;Moeck, Greg;Reddy, Ranga;Rose, Yannick;Srikumar, Ramakrishnan;Tanaka, Kelly S.E.;Williams, Daniel M.;Gros, Philippe;Pelletier, Jerry;Parr Jr., Thomas R.;Far, Adel Rafai [Bioorganic and Medicinal Chemistry,2006,vol. 14,# 17,p. 5812 - 5832]