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5-TERT-BUTYL-2-(3-FLUORO-PHENYL)-2H-PYRAZOL-3-YLAMINE synthesis

2synthesis methods
59997-51-2 Synthesis
Pivaloylacetonitrile

59997-51-2
271 suppliers
$6.00/25g

2924-16-5 Synthesis
3-Fluorophenylhydrazine hydrochloride

2924-16-5
169 suppliers
$9.00/5g

5-TERT-BUTYL-2-(3-FLUORO-PHENYL)-2H-PYRAZOL-3-YLAMINE

476637-06-6
23 suppliers
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Yield:476637-06-6 65%

Reaction Conditions:

in toluene; for 16 h;Reflux;

References:

Pan, Shulei;Zhang, Liting;Luo, Xinling;Nan, Jinshan;Yang, Wei;Bin, Huachao;Li, Yang;Huang, Qiao;Wang, Tianqi;Pan, Zhiling;Mu, Bo;Wang, Falu;Tian, Chenyu;Liu, Yang;Li, Linli;Yang, Shengyong [Journal of Medicinal Chemistry,2022,vol. 65,# 3,p. 2035 - 2058]