5-(2-Methoxyphenyl)-2H-pyrazol-3-ylamine synthesis
- Product Name:5-(2-Methoxyphenyl)-2H-pyrazol-3-ylamine
- CAS Number:149246-82-2
- Molecular formula:C10H11N3O
- Molecular Weight:189.21
35276-83-6
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149246-82-2
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Yield:149246-82-2 85%
Reaction Conditions:
with hydrazine hydrate in methanol at 150; for 0.0833333 h;Microwave irradiation;
Steps:
1.2. General procedure of microwave synthesis of pyrazoles
General procedure: A microwave tube was charged with ketonitrile (2.0 mmol), methanol (1 mL), and hydrazine monohydrate (2.6 mmol) and subjected to microwave irradiation (100 W, 150 °C) for 5 minutes. Volatiles were subsequently removed under reduced pressure. The residue was purified by either trituration with cold methanol or cyclohexane, or by using column chromatography to give the final product.
References:
Kelada, Mark;Walsh, John M. D.;Devine, Robert W.;McArdle, Patrick;Stephens, John C. [Beilstein Journal of Organic Chemistry,2018,vol. 14,p. 122 - 1228] Location in patent:supporting information
35276-83-6
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7335-26-4
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149246-82-2
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$165.00/250mg
606-45-1
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149246-82-2
43 suppliers
$165.00/250mg