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5-(3,4-dichlorophenyl)pyridin-2-amine synthesis

1synthesis methods
-

Yield:926224-90-0 62%

Reaction Conditions:

with palladium diacetate;sodium carbonate in water;N,N-dimethyl-formamide at 110; for 3 h;Suzuki coupling;

References:

Heitman, Laura H.;Van Veldhoven, Jacobus P. D.;Zweemer, Annelien M.;Ye, Kai;Brussee, Johannes;Ijzerrnan, Adriaan P. [Journal of Medicinal Chemistry,2008,vol. 51,# 15,p. 4724 - 4729] Location in patent:supporting information; experimental part