5-(3-FLUOROBENZYL)-1,3-THIAZOL-2-AMINE synthesis
- Product Name:5-(3-FLUOROBENZYL)-1,3-THIAZOL-2-AMINE
- CAS Number:884497-40-9
- Molecular formula:C10H9FN2S
- Molecular Weight:208.26
245070-85-3
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17356-08-0
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884497-40-9
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Yield:884497-40-9 43%
Reaction Conditions:
Stage #1: 3-(3-fluorophenyl)propanalwith N-chloro-succinimide;L-proline in dichloromethane at 20;
Stage #2: thiourea in ethanol;Reflux;
References:
Uto, Yoshikazu;Ogata, Tsuneaki;Harada, Jun;Kiyotsuka, Yohei;Ueno, Yuko;Miyazawa, Yuriko;Kurata, Hitoshi;Deguchi, Tsuneo;Watanabe, Nobuaki;Takagi, Toshiyuki;Wakimoto, Satoko;Okuyama, Ryo;Abe, Manabu;Kurikawa, Nobuya;Kawamura, Sayako;Yamato, Michiko;Osumi, Jun [Bioorganic and Medicinal Chemistry Letters,2009,vol. 19,# 15,p. 4151 - 4158] Location in patent:scheme or table
456-48-4
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884497-40-9
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$99.70/1g