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5-(4-Fluoro-phenyl)-1H-pyrrole-3-carboxylic acid synthesis

3synthesis methods
1H-Pyrrole-3-carboxylic acid, 5-(4-fluorophenyl)-, ethyl ester

250213-74-2
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5-(4-Fluoro-phenyl)-1H-pyrrole-3-carboxylic acid

250213-76-4
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Yield:250213-76-4 94.5%

Reaction Conditions:

with sodium hydroxide;water in ethanol; for 12 h;Heating;Hydrolysis;

References:

Pinna;Curzu;Sechi;Chelucci;Maciocco [Il Farmaco,1999,vol. 54,# 8,p. 542 - 550]