5,7-DICHLORO-BENZOFURAN-3-ONE synthesis
- Product Name:5,7-DICHLORO-BENZOFURAN-3-ONE
- CAS Number:74815-20-6
- Molecular formula:C8H4Cl2O2
- Molecular Weight:203.02
79214-30-5
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74815-20-6
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Yield:74815-20-6 30%
Reaction Conditions:
with sodium acetate in ethanol; for 0.283333 h;Reflux;
Steps:
59 Synthesis of 5,7-dichlorobenzofuran-3-one (Compound 59B)
Compound 59A (2.8 g, 12 mmol) was dissolved in ethanol (25 mL).After refluxing for 10 minutes, sodium acetate (1 g, 12 mmol) was quickly added.Continue to reflux for 7 minutes. Cool rapidly and let stand for 1 hour in an ice water bath.Water was added, and ethyl acetate was extracted three times, and washed with saturated brine.Dry over anhydrous sodium sulfate, spin dry,Separation and purification of petroleum ether/ethyl acetate (40/1) gave Compound 59B ( 615 mg, 30% yield).
References:
CN104045552,2019,B Location in patent:Paragraph 0652; 0653; 0656; 0657
120-83-2
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74815-20-6
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15080-90-7
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74815-20-6
27 suppliers
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