5,8-DICHLORO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID synthesis
- Product Name:5,8-DICHLORO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID
- CAS Number:35973-26-3
- Molecular formula:C10H5Cl2NO3
- Molecular Weight:258.06
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35973-26-3
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Yield:-
Reaction Conditions:
Stage #1: 5,8-Dichloro-4-hydroxy-quinoline-3-carboxylic acid ethyl esterwith water;potassium hydroxideReflux;
Stage #2: with hydrogenchloride in water at 20; pH=2;
References:
Li, Guo-Xiang;Liu, Zai-Qun;Luo, Xu-Yang [European Journal of Medicinal Chemistry,2010,vol. 45,# 5,p. 1821 - 1827] Location in patent:experimental part