![](/CAS/GIF/65184-39-6.gif)
5-ACETYLPYRIDINE-2-CARBOXYLIC ACID synthesis
- Product Name:5-ACETYLPYRIDINE-2-CARBOXYLIC ACID
- CAS Number:65184-39-6
- Molecular formula:C8H7NO3
- Molecular Weight:165.15
![5-Acetyl-2-cyanopyridine](/CAS/GIF/249583-84-4.gif)
249583-84-4
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![5-ACETYLPYRIDINE-2-CARBOXYLIC ACID](/CAS/GIF/65184-39-6.gif)
65184-39-6
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Yield:-
Reaction Conditions:
with hydrogenchloride;water for 2.5 h;Reflux;
Steps:
2
Step 2: (0578) 5-Acetylpicolinonitrile (146 mg, 1.0 mmol) in 5 mL of conc. HCl was heated at reflux for 2.5 h. The mixture was concentrated and dried in vacuo. The crude product 5-acetylpicolinic acid was used without further purification.
References:
MERCK SHARP & DOHME CORP.;Scott, Jack D.;Stamford, Andrew W.;Gilbert, Eric J.;Cumming, Jared N.;Iserloh, Ulrich;Misiaszek, Jeffrey A.;Li, Guoqing US2015/307465, 2015, A1 Location in patent:Paragraph 0578
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![5-ACETYLPYRIDINE-2-CARBOXYLIC ACID](/CAS/GIF/65184-39-6.gif)
65184-39-6
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$328.70/1gm:
![5-ETHYLPYRIDINE-2-CARBOXYLIC ACID](/CAS/GIF/770-08-1.gif)
770-08-1
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$140.00/1g
![5-ACETYLPYRIDINE-2-CARBOXYLIC ACID](/CAS/GIF/65184-39-6.gif)
65184-39-6
30 suppliers
$328.70/1gm: