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ChemicalBook CAS DataBase List 5-AMino-2-(piperidin-1-yl)benzonitrile

5-AMino-2-(piperidin-1-yl)benzonitrile synthesis

6synthesis methods
-

Yield:34595-33-0 92%

Reaction Conditions:

with sodium tetrahydroborate for 0.5 h;

Steps:

9 5-amino-2-(piperidin-1-yl)benzonitrile

The compound 5-nitro-2- (piperidin-1-yl) benzoic acid was subjected to reduction reaction by NaBH4 for 30 min, followed by 2.0 g of a yellow solid (Compound 11)

References:

CN106892871,2017,A Location in patent:Paragraph 0135; 0138; 0139