![](/CAS/GIF/5451-09-2.gif)
5-Aminolevulinic acid hydrochloride synthesis
- Product Name:5-Aminolevulinic acid hydrochloride
- CAS Number:5451-09-2
- Molecular formula:C5H10ClNO3
- Molecular Weight:167.59
Shrestha-dawadi, Prativa Bade; Lugtenburg, Johan. Preparation of [1,2,3,4,5-13C5]-5-amino-4-oxopentanoic acid (ALA) - design of a synthetic scheme to prepare any 13C- and 15N-isotopomer with high isotopic enrichment. European Journal of Organic Chemistry. Issue 23. Pages 4654-4663. 2003.
![5-phthaliMidolevulinic acid](/CAS/20150408/GIF/92632-81-0.gif)
92632-81-0
26 suppliers
inquiry
![5-Aminolevulinic acid hydrochloride](/CAS/GIF/5451-09-2.gif)
5451-09-2
496 suppliers
$16.80/1G
Yield:5451-09-2 96.6%
Reaction Conditions:
with hydrogenchloride in water; for 6 h;Reflux;
Steps:
2.1; 2.1-1; 2.2; 2.1-2; 2.3-2.17; 2.1-3; 2.5.3; 3
Dissolve 2.00 g of 5-phthalimide levulinic acid obtained in the previous step with 40 ml of 6N hydrochloric acid and heat it for reaction at reflux for 6 hours, decolorize and filter on activated carbon, distill under reduced pressure to remove water to the end, and recrystallize the remainder with acetone , To obtain 1.24 g of solid. According to the proton nuclear magnetic resonance spectrum data, the obtained solid is determined to be 5-aminolevulinic acid hydrochloride, with a yield of 96.6% (calculated as 5-phthalimidolevulinic acid); mp: 149°C, purity ( HPLC, a/a%) 99.9%.
References:
CN111592484,2020,A Location in patent:Paragraph 0060; 0062-0063; 0065-0066; 0068-0069; 0071-0072
![5-Benzamido-4-oxopentanoic acid](/CAS/20180629/GIF/102872-00-4.gif)
102872-00-4
9 suppliers
inquiry
![5-Aminolevulinic acid hydrochloride](/CAS/GIF/5451-09-2.gif)
5451-09-2
496 suppliers
$16.80/1G
![Pentanoic acid, 5-(acetylamino)-4-oxo-](/CAS/20200331/GIF/20238-92-0.gif)
20238-92-0
0 suppliers
inquiry
![5-Aminolevulinic acid hydrochloride](/CAS/GIF/5451-09-2.gif)
5451-09-2
496 suppliers
$16.80/1G
![Hexanedioic acid, 2-(acetylamino)-3-oxo-, diethyl ester (9CI)](/CAS/20210305/GIF/839724-53-7.gif)
839724-53-7
0 suppliers
inquiry
![5-Aminolevulinic acid hydrochloride](/CAS/GIF/5451-09-2.gif)
5451-09-2
496 suppliers
$16.80/1G
![methyl 5-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-4-oxopentanoate](/CAS/GIF/109258-71-1.gif)
109258-71-1
31 suppliers
$263.00/500mg
![5-Aminolevulinic acid hydrochloride](/CAS/GIF/5451-09-2.gif)
5451-09-2
496 suppliers
$16.80/1G