5-bromo-1-(tert-butyldimethylsilyl)-1h-indole synthesis
- Product Name:5-bromo-1-(tert-butyldimethylsilyl)-1h-indole
- CAS Number:331432-91-8
- Molecular formula:C14H20BrNSi
- Molecular Weight:310.3
10075-50-0
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Yield:331432-91-8 98%
Reaction Conditions:
Stage #1: 5-bromo-1H-indolewith lithium hexamethyldisilazane in tetrahydrofuran;
Stage #2: tert-butyldimethylsilyl chloride
References:
Carter, David S.;Cai, Hai-Ying;Lee, Eun Kyung;Iyer, Pravin S.;Lucas, Matthew C.;Roetz, Ralf;Schoenfeld, Ryan C.;Weikert, Robert J. [Bioorganic and Medicinal Chemistry Letters,2010,vol. 20,# 13,p. 3941 - 3945] Location in patent:scheme or table
1152720-75-6
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